Wednesday November 21, 2018

Fish during pregnancy may protect baby from asthma

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Pregnancy
Fish during pregnancy may protect baby from asthma
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New York, Oct 3: Women who consume fish during pregnancy are just as likley to protect their offspring from developing asthma as those who consume fish oil supplements, suggests a new study.

Pregnant women who consume high doses of omega-3 fatty acids in the third trimester may help protect their kids from developing breathing problems in their early childhood, according to the study.

“With almost equal to slightly higher cost, consuming 8-12 ounces (2-3 servings) of fish with low mercury levels a week not only may attain the same asthma protection, but also strengthen the nutritional benefits to infant growth and development,” said Richard Lockey, Professor at the University of South Florida in the US.

The study, published in the Journal of Allergy and Clinical Immunology: In Practice, was conducted in three groups of women in their third trimester.

The first group consumed omega-3 fatty acids from fish oil daily while the second group took a placebo. The third group was named the “no oil” group who were allowed to consume either fish or fish oil supplements as per their choices.

The researchers found that the children in the fish oil and the “no oil” groups took less asthma medication as they aged to 24 years old, inferring both groups developed less asthma.

“Omega-3 fatty acids cannot be synthesised by humans and therefore are essential nutrients which are derived exclusively from marine sources,” said iChen Hsing Lin from the University of South Florida.(IANS)

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Omega-3 Fatty Acids in Diet can Prevent Cancer From Spreading

While dietary consumption of omega-3 fatty acids can lead to EDP-EAs, for those with cancer, something concentrated and fast acting is needed

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Food
Gene-editing can't do everything. (IANS)

While eating foods rich in omega-3 fatty acids, such as fatty fish, certain nuts and seeds, have been known to prevent heart diseases and arthritis, a new research, led by one of Indian-origin, showed that omega-3 fatty byproducts may also have anti-cancer effects.

The new study, led by Aditi Das from University of Illinois at Urbana-Champaign, US, showed that when the human body metabolises omega-3 fatty acids, it produces a class of molecules called endocannabinoid epoxides, or EDP-EAs. These have anti-inflammatory properties and can inhibit cancer’s growth and spread.

The EDP-EAs have similar properties to cannabinoids found in marijuana — but without the psychotropic effects — and they target the same receptor in the body that cannabis does.

“We have a built-in endocannabinoid system which is anti-inflammatory and pain-reducing. Now we see it is also anti-cancer, stopping the cells from proliferating or migrating,” said study leader Aditi Das from University of Illinois at Urbana-Champaign.

The higher concentrations of EDP-EAs did kill cancer cells, but not as effectively as other chemotherapeutic drugs on the market.
The higher concentrations of EDP-EAs did kill cancer cells, but not as effectively as other chemotherapeutic drugs on the market. Pixabay

“These molecules could address multiple problems: cancer, inflammation and pain,” Das added.

For the study, published in the Journal of Medicinal Chemistry, the team studied the effect of the molecule in mice with tumours of osteosarcoma — a bone cancer that is not only painful but also difficult to treat.

The results showed that the endocannabinoids slowed the growth of tumours and blood vessels, inhibited the cancer cells from migrating and caused cancer cell death.

The higher concentrations of EDP-EAs did kill cancer cells, but not as effectively as other chemotherapeutic drugs on the market. But, the compounds slowed tumour growth by inhibiting new blood vessels from forming to supply the tumour with nutrients. They also prevented interactions between the cells, and most significantly, they appeared to stop cancerous cells from migrating.

Also Read: Cancer-Causing Chemical Found In Odisha Fish Sample

While dietary consumption of omega-3 fatty acids can lead to EDP-EAs, for those with cancer, something concentrated and fast acting is needed, Das said.

“That’s where the endocannabinoid epoxide derivatives come into play – you could make a concentrated dose of the exact compound that’s most effective against the cancer. You could also mix this with other drugs such as chemotherapies,” she added. (IANS)