Tuesday October 15, 2019

Flavoured E-Cigarettes Affect Airways, Worsen Asthma

Certain flavoured e-cigarettes, even without nicotine, may change how airways, affected by an allergic disease, function, thus worsening the severity of asthma

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e-cigarettes, flavoured, asthma, airways
A flavour multipack for the Juul vaping device. Sweet-flavored electronic cigarettes promote youth vaping. Wikimedia Commons

Certain flavoured e-cigarettes, even without nicotine, may change how airways, affected by an allergic disease, function, thus worsening the severity of diseases such as asthma, say researchers.

For the first time, a model of asthma was used to investigate the effect of a range of popular e-cigarette flavours, with and without nicotine.

“This is especially important for those with respiratory disease, whom are vulnerable to the effects of smoking,” Dr Chapman said.

“The majority of e-cigarette smokers use flavoured liquids but there is some evidence that flavour additives can be toxic when inhaled,” said Dr David Chapman from from the University of Technology Sydney (UTS).

The use of e-cigarettes has dramatically increased in the past few years, especially among younger smokers globally.

e-cigarettes, flavoured, asthma, airways
The U.S. Centers for Disease Control and Prevention (CDC) said Friday that they were investigating 215 cases of a serious lung disease possibly related to the use of e-cigarettes. VOA

Despite the suggestion they are a healthier alternative to tobacco cigarettes, there is a lack of evidence in both animal studies and human data on the effect of e-cigarettes on lung function.

The researchers found that some flavoured e-cigarettes, even in the absence of nicotine, can worsen disease severity.

“The exact effects on features of asthma were dependent upon the specific flavour, suggesting not all flavoured e-cigarettes will have the same consequences on lung health,” Dr Chapman said in the study published in Scientific Reports.

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In this study, the flavour Black Licorice exaggerated airway inflammation whereas Cinnacide had the opposite effect, suppressing airway inflammation.

The researchers didn’t analyse the liquids directly, to confirm what they contained, however there is evidence from previous research that flavours categorised as “buttery/creamy” and “cinnamon”, which likely include “Banana Pudding” and “Cinnacide”, respectively, are toxic.

Caution should be taken in promoting the use of flavoured e-cigarettes to patients with respiratory disease such as asthma and that policy makers should consider restricting the use of flavoured e-cigarettes, the team added. (IANS)

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Carcinogen Metals Like- Lead, Nickel Found in E-Cigarettes

A team of US scientists has found that the concentration of carcinogen metals like lead, nickel, iron and copper in electronic cigarette aerosols, or vapour, has increased

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e-cigarettes, lead, nickel, carcinogen, metal
Prolonged exposure to lead could produce vomiting, diarrhoea, cardiovascular effects, and lung cancer. Pixabay

A team of US scientists has found that the concentration of carcinogen metals like lead, nickel, iron and copper in electronic cigarette aerosols, or vapour, has increased since tank-style electronic cigarettes were introduced in 2013.

Electronic cigarettes, which consist of a battery, atomizing unit and refill the fluid, are now available in new tank-style designs, equipped with more powerful batteries and larger capacity reservoirs for storing more refill fluid.

But the high-power batteries and atomizers used in these new styles can alter the metal concentrations that transfer into the aerosol, said researchers from the University of California, Riverside.

“These tank-style e-cigarettes operate at higher voltage and power, resulting in higher concentrations of metals, such as lead, nickel, iron, and copper, in their aerosols.

“Most of the metals in e-cigarette aerosols likely come from the nichrome wire, tin solder joints, brass clamps, insulating sheaths, and wicks, components of the atomizer unit,” said Monique Williams, a post-doctoral researcher and the first author of the paper that appeared in the journal Scientific Reports.

The researchers examined six tank-style electronic cigarettes and found all the aerosols had metals that appeared to originate in the atomizers.

Further, they found the model with fewest metal parts in its atomizer had the fewest metals in its aerosol.

Of the 19 metals they screened, aluminium, calcium, chromium, copper, iron, lead, magnesium, nickel, silicon, tin and zinc were from components in the atomizing units.

“We found the concentrations of chromium, copper, lead, nickel, and zinc exceeded the proposed permissible exposure limit from the Occupational Safety and Health Administration,” Williams said.

e-cigarettes, lead, nickel, carcinogen, metal
Prolonged exposure to chromium could cause gastrointestinal effects, nasal and lung cancer, respiratory irritation, and lung function impairment. Wikimedia Commons

Chromium, lead, and nickel are known as carcinogens. Prolonged exposure to chromium could cause gastrointestinal effects, nasal and lung cancer, respiratory irritation, and lung function impairment.

Prolonged exposure to lead could produce vomiting, diarrhoea, cardiovascular effects, and lung cancer.

Nickel inhalation could cause lung disease, damage to the nasal cavity, lung irritation, lung inflammation, hyperplasia in pulmonary cells and fibrosis.

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The researchers have analyzed the following six tanks and their atomizers: Kangertech Protank, Aspire Nautilus tank, Kanger T3S tank, Tsunami 2.4, Smok tank and Clone.

“The presence of heavy metals, including some known carcinogens, in e-cigarette aerosols is concerning because with prolonged exposure they could cause adverse health effects,” said Prue Talbot, a professor of cell biology, who led the research team. (IANS)