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High Sugar Levels In Mothers Can Risk Obesity In Child: Study

Lowering a mother's blood sugar during her pregnancy reduces the birth weight of the child.

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Risk of death 5 times higher in epileptic pregnant women: Study. Pixabay
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Babies born to woman with higher blood sugar levels during pregnancy could be at significantly greater long-term risk of obesity – even more than a decade later, a study has found.

The higher the woman’s blood sugar, the greater the risk of her child being obese.

The researchers suspect that epigenetic changes are likely to be influencing these long-term outcomes and those changes begin quite early in pregnancy.

Pregnancy
Maternal high blood sugar linked to obesity risk in kids Pixabay

“The mother’s blood sugar level during pregnancy is an independent contributor to the child’s weight and risk of being obese later in childhood,” said Boyd Metzger, professor at the Northwestern University Feinberg School of Medicine.

In addition, mothers with higher-than-normal blood sugar during pregnancy — even if not at the level of gestational diabetes — also were significantly more likely to have developed Type-2 diabetes a decade after pregnancy than their counterparts without high blood sugar, the researchers said, in the paper published in the journal JAMA.

Lowering a mother’s blood sugar during her pregnancy reduces the birth weight of the child, as well as the risk of pre-eclampsia — potentially life-threatening condition in which the mother has high blood pressure that affects her and the baby.

Pregnancy
The higher the woman’s blood sugar, the greater the risk of her child being obese. Pixabay

If not regulated on time, these can potentially increase the number of women and children at risk of acquiring lifelong chronic medical conditions.

“The results are important because they demonstrate that even women with mild hyperglycemia during pregnancy and their offspring are at risk of harmful maternal and child health outcomes,” said coauthor Wendy Brickman, associate professor at Feinberg.

“Research is needed to identify interventions that will improve the health outcomes of these women and children,” Brickman said.

Also Read: Weight Loss Tip- Chinese Medicine Ingredient May Help Reduce Obesity

The study evaluated children 10 to 14 years after birth in 10 clinical centers in seven countries: the US, Canada, Israel, the UK, Hong Kong, Thailand and Barbados.

The study included 4,697 mothers and 4,832 children. (IANS)

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First Successful Case Of Womb Transplant in Brazil

In the Brazilian case, the recipient had been born without a uterus due to a condition called Mayer-Rokitansky-Küster-Hauser syndrome. The donor was 45 and died of a stroke.

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Womb Transplant
Medical team hold the first baby born via uterus transplant from a deceased donor at the hospital in Sao Paulo, Brazil. VOA

A woman in Brazil who received a womb transplanted from a deceased donor has given birth to a baby girl in the first successful case of its kind, doctors reported.

The case, published in The Lancet medical journal, involved connecting veins from the donor uterus with the recipient’s veins, as well as linking arteries, ligaments and vaginal canals.

It comes after 10 previously known cases of uterus transplants from deceased donors – in the United States, the Czech Republic and Turkey – failed to produce a live birth.

The girl born in the Brazilian case was delivered via caesarean section at 35 weeks and three days, and weighed 2,550 grams (nearly 6 lbs), the case study said.

Dani Ejzenberg, a doctor at Brazil’s Sao Paulo University hospital who led the research, said the transplant – carried out in September 2016 when the recipient was 32 – shows the technique is feasible and could offer women with uterine infertility access to a larger pool of potential donors.

Womb
. The woman’s previously fertilized and frozen eggs were implanted after seven months and 10 days later she was confirmed pregnant.. Pixabay

The current norm for receiving a womb transplant is that the organ would come from a live family member willing to donate it.

“The numbers of people willing and committed to donate organs upon their own deaths are far larger than those of live donors, offering a much wider potential donor population,” Ejzenberg said in a statement about the results.

She added, however, that the outcomes and effects of womb donations from live and deceased donors have yet to be compared, and said the technique could still be refined and optimised.

The first baby born after a live donor womb transplant was in Sweden in 2013. Scientists have so far reported a total of 39 procedures of this kind, resulting in 11 live births.

Experts estimate that infertility affects around 10 to 15 percent of couples of reproductive age worldwide. Of this group, around one in 500 women have uterine problems.

Before uterus transplants became possible, the only options to have a child were adoption or surrogacy.

Infants, baby, WOmb
The case, published in The Lancet medical journal, involved connecting veins from the donor uterus with the recipient’s veins. Pixabay

In the Brazilian case, the recipient had been born without a uterus due to a condition called Mayer-Rokitansky-Küster-Hauser syndrome. The donor was 45 and died of a stroke.

Also Read: Pregnancy is Possible For Survivors of Breast Cancer

Five months after the transplant, Ejzenberg’s team wrote, the uterus showed no signs of rejection, ultrasound scans were normal, and the recipient was having regular menstruation. The woman’s previously fertilized and frozen eggs were implanted after seven months and 10 days later she was confirmed pregnant.

At seven months and 20 days – when the case study report was submitted to The Lancet – the baby girl was continuing to breastfeed and weighed 7.2 kg (16 lb). (VOA)