Monday December 16, 2019

Older Adults With Poor Cognitive Functions At A Higher Risk of Tooth Loss

"Our study suggested a close link between cognitive function and oral health in older adults," said Jianhua Wu, Researcher at the University of Leeds in Britain. 

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"The findings indicate that an improvement in cognitive function could potentially improve oral health and reduce the risk of tooth loss in the ageing population," said Wu. Pixabay

Older adults with poor cognitive function are found to have impaired oral health and higher risk of tooth loss later, says a study.

According to the study, there was a clear association between cognitive function and tooth loss when cognitive function score was categorised into quintiles.

The study, published in the Community Dentistry & Oral Epidemiology, showed people in the lowest quintile reflecting poorer cognitive function had 39 per cent higher odds of tooth loss than those in the highest quintile.

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According to the study, there was a clear association between cognitive function and tooth loss when cognitive function score was categorised into quintiles.
Pixabay

“Our study suggested a close link between cognitive function and oral health in older adults,” said Jianhua Wu, Researcher at the University of Leeds in Britain.

“The findings indicate that an improvement in cognitive function could potentially improve oral health and reduce the risk of tooth loss in the ageing population,” said Wu.

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The study included 4,416 adults aged 50 years and above.

According to previous studies, older adults with just 10-19 teeth are at a higher risk of malnutrition in addition to higher rates of weight loss and lower appetite. They are also at increased risk for dementia and/or depression. (IANS)

Next Story

This Protein in the Human Brain Can Protect Against Alzheimer’s disease

Brain protein that could protect against Alzheimer's disease

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Human Brain
Immune cells in the brain, called microglia, play a critical role in Alzheimer's disease. Pixabay

Researchers have found that a protein that regulates white blood cells in the human brain could protect against Alzheimer’s disease.

The results published in the journal Communications Biology suggest that this protein, called CD33, could have important implications in the fight against Alzheimer’s disease.

“Immune cells in the brain, called microglia, play a critical role in Alzheimer’s disease,” explained study co-author Matthew Macauley, Assistant Professor at University of Alberta in Edmonton, Canada.

“They can be harmful or protective. Swaying microglia from a harmful to protective state could be the key to treating the disease,” Macauley added.

Scientists have identified the CD33 protein as a factor that may decrease a person’s likelihood of Alzheimer’s disease.

Brain
CD33 protein in the brain plays a crucial role in modulating the function of microglia. Pixabay

Now, Macauley’s research has shown that the most common type of CD33 protein plays a crucial role in modulating the function of microglia.

“The fact that CD33 is found on microglia suggests that immune cells can protect the brain from Alzheimer’s disease under the right circumstances,” said Abhishek Bhattacherjee, first author and postdoctoral fellow in the Macauley lab.

Alzheimer’s disease affects more than 44 million people around the world.

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“These findings set the stage for future testing of a causal relationship between CD33 and Alzheimer’s Disease, as well as testing therapeutic strategies to sway microglia from harmful to protecting against the disease – by targeting CD33,” said Macauley.

“Microglia have the potential to ‘clean up’ the neurodegenerative plaques, through a process called phagocytosis — so a therapy to harness this ability to slow down or reverse Alzheimer’s disease can be envisioned,” Macauley said. (IANS)