Sunday October 20, 2019

Paracetamol During Pregnancy Can Risk Child’s Behaviour

Women who take paracetamol during pregnancy are at risk of having children with behaviour problems, warn researchers

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paracetamol, pregnancy, risk, behaviour
The study found an association between paracetamol intake and behavioural issues in children including hyperactivity and attention-deficit disorder. Pixabay

Women who take paracetamol during pregnancy are at risk of having children with behaviour problems, warn researchers.

The study, published in the journal Paediatric and Perinatal Epidemiology, examined whether there were any effects of taking paracetamol in mid-pregnancy and the behaviour of the offspring between the ages of six month and 11 years, with memory and IQ tested up until the age of 17.

“Our findings add to a series of results concerning evidence of the possible adverse effects of taking paracetamol during pregnancy such as issues with asthma or behaviour in the offspring,” said study lead author Jean Golding, Professor at the University of Bristol in the UK.

“It reinforces the advice that women should be cautious when taking medication during pregnancy and to seek medical advice where necessary,” Golding said.

Using questionnaire and school information from Bristol’s Children of the 90s study, researchers examined 14,000 children.

paracetamol, pregnancy, risk, behaviour
Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells. Pixabay

When they were seven months pregnant, 43 per cent of their mothers said they had taken paracetamol “sometimes” or more often during the previous three months.

The researchers examined results of the children’s memory, IQ and pre-school development tests, temperament and behaviour measures.

The study found an association between paracetamol intake and behavioural issues in children including hyperactivity and attention-deficit disorder.

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However, this was no longer the case by the time the children reached the end of primary school.

According to the reseachers, boys appeared to be more susceptible than girls to the possible behavioural effects of the drug.

“It is important that our findings are tested in other studies – we were not in a position to show a causal link, rather an association between two outcomes,” Golding added. (IANS)

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Children Born to Women with Hyperemesis may be at Increased Risk of Autism

This could lead to dangerous dehydration and inadequate nutrition during pregnancy

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Mothers, Morning Sickness, Pregnancy
Affected women experience intense nausea and are unable to keep down food and fluids. Pixabay

Children whose mothers had hyperemesis gravidarum, a severe form of morning sickness, during pregnancy were 53 per cent more likely to be diagnosed with an autism spectrum disorder, a study said.

Hyperemesis gravidarum occurs in less than five per cent of pregnancies. Affected women experience intense nausea and are unable to keep down food and fluids.

This could lead to dangerous dehydration and inadequate nutrition during pregnancy.

“This study is important because it suggests that children born to women with hyperemesis may be at an increased risk of autism,” said the study’s lead author Darios Getahun, Kaiser Permanente Southern California Department of Research and Evaluation.

Mothers, Morning Sickness, Pregnancy
Hyperemesis gravidarum occurs in less than five per cent of pregnancies. Pixabay

“Awareness of this association may create the opportunity for earlier diagnosis and intervention in children at risk of autism,” Getahun said,

For the study published in the American Journal of Perinatology, researchers reviewed the electronic health records of nearly 500,000 pregnant women and their children born between 1991-2014 in Southern California.

They compared children whose mothers had a diagnosis of hyperemesis gravidarum during pregnancy to those whose mothers did not.

The researchers found that exposure to hyperemesis gravidarum was associated with increased risk of autism when the disease was diagnosed during the first and second trimesters of pregnancy, but not when it was diagnosed only in the third trimester.

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Exposure to the disease was associated with the risk of autism regardless of the severity of the mother’s hyperemesis gravidarum, the study said.

The results are consistent with the hypothesis that women experiencing hyperemesis gravidarum have a poor nutritional intake, which might, in turn lead to potential long-term neurodevelopment impairment in their children. (IANS)