Thursday, April 22, 2021
Home Life Style Health & Fitness Researchers: Three Common Antiviral Medications Possibly Efficacious Against COVID

Researchers: Three Common Antiviral Medications Possibly Efficacious Against COVID

The researchers utilized a variety of cell lines that represented potential targets for SARS-CoV-2 infection in the human body

A team of researchers has found that three commonly used antiviral and antimalarial drugs are effective in vitro at preventing replication of SARS-CoV-2, the virus that causes Covid-19.

The study, published in the journal ACS Omega, looked at three antiviral drugs that have proven effective against Ebola and the Marburg virus — tilorone, quinacrine, and pyronaridine.

Follow NewsGram on Twitter to stay updated about the World news.

“We were looking for compounds that could block the entry of the virus into the cell,” said researcher Anna Puhl from the University of North Carolina in the US.

Antiviral
The research examined three antiviral drugs that have been shown to be effective against Ebola and the Marburg virus. Pixabay

“We chose these compounds because we know that other antivirals which successfully act against Ebola are also effective inhibitors of SARS-CoV-2,” Puhl added.

For the study, the compounds were tested in vitro against SARS-CoV-2, as well as against a common cold virus (HCV 229E) and murine hepatitis virus (MHV).

The researchers utilized a variety of cell lines that represented potential targets for SARS-CoV-2 infection in the human body. They infected the cell lines with the different viruses and then looked at how well the compounds prevented viral replication in the cells.

The team found that the results were mixed, with the compounds’ effectiveness depending upon whether they were used in human-derived cell lines versus monkey-derived cell lines, known as Vero cell lines.

ALSO READ: People Who Recieve Flu Shot Less Likely To Test COVID-19 Positive: Study

“In the human-derived cell lines, we found that all three compounds worked similarly to remdesivir, which is currently being used to treat Covid-19,” the researchers said.

The next steps for the research include testing the compounds’ effectiveness in a mouse model and further work on understanding how they inhibit viral replication. (IANS/KB)

STAY CONNECTED

19,507FansLike
362FollowersFollow
1,773FollowersFollow

Most Popular

All In The Mind: The State Of Mental Health In Corporate India

A study highlighting the role of the workplace in causing, furthering, and perpetuating mental illness, launched by Gi Group India, a leading human capital...

Instagram’s New Feature To Protect People From Abusive DMs

Facebook-owned Instagram on Wednesday announced a new feature to protect people from seeing abusive direct messages (DMs), as well as the ability to prevent...

Spiritual Power To Guard: Devotees Of Lord Ram Spread Message Of Covid19 Norms

In the wake of Bengaluru witnessing an unprecedented surge in Covid cases since the last month, devotees of Lord Ram wore costumes of Ram,...

Know What Lies Behind Tehreek-e-Labaik Pakistan’s Challenge To The State?

Pakistan's government has been put under a severe challenge and test by an Islamist party, which has wreaked havoc in the country this week...

Religious Hardliners Bring Pakistan Govt To A Standstill

The current ruling government of Pakistan, led by Prime Minister Imran Khan, may have come with a vision of progress and open-mindedness to create...

Football And Its Evolution

By- Khushi Bisht Football, also known as soccer, has a long and illustrious history. According to a global study conducted by FIFA, over 250 million...

Nikola Tesla: A Man Ahead Of His Time

BY- JAYA CHOUDHARY When discussing the greatest inventors of all time, Nikola Tesla is sometimes overlooked in history lessons at school. We often hear names...

The Best Documentaries You Can Watch On The Internet Today

By Nauman Abrar As children, most of us disliked documentaries because they were long, boring, very close to reality, and based on the truth. That...

Recent Comments