Friday June 22, 2018

Scientists find a new way to preserve sperm Stem Cells that can enable boys to undergo Cancer Treatment without risking their Fertility

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Joyce Endresen wears an Optune therapy device for brain cancer, as she speaks on a phone at work in Aurora, Illinois, March 29, 2017. She was diagnosed in December 2014 with Glioblastoma. After two surgeries to remove the tumor as well as radiation and chemotherapy Endresen is now trying the new "sci-fi" cap therapy, VOA
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New York, April 10, 2017: US scientists have found a promising way to preserve sperm stem cells that could enable boys to undergo cancer treatment without risking their fertility.

Adult men can have their sperm frozen before undergoing radiation or chemotherapy — cancer treatment that can render sperm infertile.

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But boys who have not been through puberty can only have sperm stem cells removed and frozen in anticipation of technology that could culture the cells and place them back in the testes, where they produce sperm after puberty.

“I think it’s going to become the standard by which everybody cultures their cells, including trying to develop conditions for human cells,” said Jon Oatley, Associate Professor at Washington State University.

For the study, published in the journal Stem Cell Reports, the team worked with prepubescent mouse pups and put a fluorescent tag on a gene specific to stem cells, which revealed the process of a stem cell differentiating to create the progenitors that eventually become sperm.

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Initially, the stem cells creating energy through one method, called glycolysis, then switching to the second method, called oxidative phosphorylation, which produces free radicals — reactive forms of oxygen that can be particularly harmful to a cell’s DNA.

Thus, the team tried to change the culture environment to favour glycolysis.

By lowering the oxygen in the culture (that is by adding nitrogen to cut oxygen by more than half), the researchers found they could dramatically improve the percentage of stem cells capable of making normal sperm when put back into the testes.

Where before only five per cent of the cells remained viable after six months, now 40 per cent were viable, the researchers noted.

“We’re getting an eight-fold improvement,” Oatley added. (IANS)

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FIFA World Cup 2018: Indian Cuisine becomes the most sought after in Moscow

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Indian cuisine in FIFA World cup
Indian dishes available in Moscow during FIFA World Cup 2018, representational image, wikimedia commons

June 17, 2018:

Restaurateurs Prodyut and Sumana Mukherjee have not only brought Indian cuisine to the ongoing FIFA World Cup 2018 here but also plan to dish out free dinner to countrymen if Argentina wins the trophy on July 15.

Based in Moscow for the last 27 years, Prodyut and Sumana run two Indian eateries, “Talk Of The Town” and “Fusion Plaza”.

You may like to read more on Indian cuisine: Indian ‘masala’, among other condiments spicing up global food palate.

Both restaurants serve popular Indian dishes like butter chicken, kebabs and a varied vegetarian spread.

During the ongoing FIFA World Cup 2018, there will be 25 per cent discount for those who will possess a Fan ID (required to watch World Cup games).

There will also be gifts and contests on offers during matches in both the restaurants to celebrate the event.

The Mukherjees, hailing from Kolkata, are die-hard fans of Argentina. Despite Albiceleste drawing 1-1 with Iceland in their group opener with Lionel Messi failing to sparkle, they believe Jorge Sampaoli’s team can go the distance.

“I am an Argentina fan. I have booked tickets for a quarterfinal match, a semifinal and of course the final. If Argentina goes on to lift

During the World Cup, there will be 25 per cent discount for those who will possess a Fan ID (required to watch World Cup games).

There will also be gifts and contests on offers during matches in both the restaurants to celebrate the event.

FIFA World Cup 2018 Russia
FIFA World Cup 2018, Wikimedia Commons.

“We have been waiting for this World Cup. Indians come in large numbers during the World Cup and we wanted these eateries to be a melting point,” he added.

According to Cutting Edge Events, FIFA’s official sales agency in India for the 2018 World Cup, India is amongst the top 10 countries in terms of number of match tickets bought.

Read more about Indian cuisine abroad: Hindoostane Coffee House: London’s First Indian Restaurant.

Prodyut came to Moscow to study engineering and later started working for a pharmaceutical company here before trying his hand in business. Besides running the two restaurants with the help of his wife, he was into the distribution of pharmaceutical products.

“After Russia won the first match of the World Cup, the footfall has gone up considerably. The Indians are also flooding in after the 6-9 p.m. game. That is the time both my restaurants remain full,” Prodyut said.

There are also plans to rope in registered fan clubs of Latin American countries, who will throng the restaurants during matches and then follow it up with after-game parties till the wee hours.

“I did get in touch with some of the fan clubs I had prior idea about. They agreed to come over and celebrate the games at our joints. Those will be gala nights when both eateries will remain open all night for them to enjoy,” Prodyut said.

Watching the World Cup is a dream come true for the couple, Sumana said.

“We want to make the Indians who have come here to witness the spectacle and feel at home too. We always extend a helping hand and since we are from West Bengal, we make special dishes for those who come from Bengal,” she added. (IANS)