Wednesday April 25, 2018

Stress during Pregnancy may cause Female Children to Exhibit binge-eating-like behaviour in Adulthood: Study

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Stress during Pregnancy may cause Female Children to exhibit binge-eating-like behaviour in Adulthood. Pixabay
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New York, June 1, 2017: Stress during pregnancy may cause female children to exhibit binge-eating-like behaviour in adulthood, a study conducted on mice has showed.

Although stressed mothers passed along binge eating-related epigenetic tags on their DNA, the mouse pups’ tendency to binge surfaced only when they too were subjected to stressful situations, the researchers said.

“The price we pay later in life — whether it’s psychiatric disorders, metabolic syndromes, or heart-related illnesses — is heavily impacted by the way your brain was programmed early in life,” said Alon Chen, a neurobiologist at the Weizmann Institute in Israel.

“We have established a model where we can actually show that early life stress increases the likelihood of binge eating in females,” Chen said.

For the study, detailed in the journal Cell Metabolism, the researchers genetically engineered a line of mice, where they manipulated the hormone system that controls cortisol — stress hormones — release to increase the anxiety levels of pregnant mothers during their third trimester.

The mouse pups’ tendency to binge only surfaced when they were placed in a stressful situation where the researchers restricted their access to food.

In addition, measuring the eating habits of stressed mice showed that those born to stressed mothers were more likely to eat large amounts of food during short windows of time.

However, putting the young mice on a diet with “balanced” levels of nutrients such as Vitamin B12 and folate, the researchers were able to prevent their binge eating.

All of this underscores the importance of avoiding stressful situations as much as possible during pregnancy, the researchers added. (IANS)

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  • vedika kakar

    All those grandmother sayings have finally come true!
    But these habits develop later on and this cld be a way of putting the mother only to blame which is incorrect

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Prolonged paracetamol use in pregnancy may up autism, ADHD risk

While there is also a 20 percent increase in relative risk for ASD, compared to those who did not take the medications

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Long-term use of paracetamol during pregnancy is associated with the risk of neurodevelopmental disorders like attention deficit hyperactivity disorder (ADHD) and autistic spectrum disorder (ASD), a study has found.

Previous studies showed that long-term administration of low doses of paracetamol also known as acetaminophen may affect the development of the fetal nervous system. This effect is often seen years after exposure during childhood.

Protein responsible for postpartum depression in pregnancy found
Paracetamol can harm infants. IANS

The new study, appearing in the American Journal of Epidemiology, showed that prolonged exposure to acetaminophen found in the commonly used drug for the treatment of pain and fever, during pregnancy is associated with a 30 per cent increase in relative risk for ADHD.

While there is also a 20 per cent increase in relative risk for ASD, compared to those who did not take the medications. “The findings suggest an association between prolonged acetaminophen use and an increase in the risk of autism and ADHD,” said Ilan Matok, from the Hebrew University of Jerusalem in Israel.

Also Read: 5 Healthy Ways To Get Back In Shape After Pregnancy

For the new research, the team conducted a systematic review and meta-analysis 1,32,738 mother and child pairs with a follow-up period of three to 11 years.

The researchers believe that it is important to understand that pain and fever during pregnancy can have a detrimental effect on the developing foetus, but acetaminophen is still considered a safe drug for use during pregnancy.

Paracetamol can cause ADHD in children. Pixabay

Therefore, if a pregnant woman has fever and/or pain, acetaminophen can be taken for a short period, and if the fever or pain continues beyond that, she should consult her physician regarding further treatment.

“While the unnecessary use of any medication should be avoided in pregnancy, we believe our findings should not alter current practice and women should not avoid the use of short-term acetaminophen when clinically needed,” Matok said. IANS