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Uganda To Start Experimental Vaccine For Ebola Along With DRC

The Ebola virus causes a severe and often fatal hemorrhagic fever.

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Congo, Uganda, ebola
A Congolese health worker administers Ebola vaccine to a boy who had contact with an Ebola sufferer in the village of Mangina in North Kivu province of the Democratic Republic of the Congo. VOA

Uganda will begin administering the experimental Ebola vaccine to approximately 2,000 health care and front-line workers along its border with the Democratic Republic of Congo on Monday, the Ministry of Health said.

Uganda has no confirmed cases of Ebola, but as the threat worsens in the DRC, the preventive measure is seen as necessary because of heavy border traffic. More than 20,000 people cross from the DRC into Uganda and back every week, the ministry says.

“The public high risk of cross-border transmission of Ebola to Uganda was assessed to be very high at national level,” said Jane Ruth Aceng, Uganda’s minister for health. “Hence, the need to protect our health workers with this vaccine. Currently in Uganda, we have 2,100 doses of the vaccine available at the National Medical Stores and preparations are in high gear, including training of the health workers that are to be targeted.”

Congo, Uganda, ebola
A health care worker from the World Health Organization, left, gives an Ebola vaccination to a front line aid worker who will then vaccinate people who might potentially have the virus, in Mbandaka, Congo, May 30, 2018.
VOA

Many of those crossing the border are from the DRC’s North Kivu province, about 100 kilometers (62 miles) from the Ugandan border, where armed conflict has made fighting the Ebola outbreak a challenge.

The vaccine, known as rVSV, has been used during recent outbreaks in Congo, Guinea and Sierra Leone, and is currently being dispensed in North Kivu.

Uganda’s Health Ministry says the Ebola vaccine will be given with the consent of Uganda’s health workers, since it is being used outside of clinical trials.

Congo, Uganda, ebola
Photo taken Sept 9, 2018, shows health workers walking with a boy suspected of having the Ebola virus at an Ebola treatment centre in Beni, Eastern Congo. VOA

Despite being experimental, the vaccine is absolutely safe, Aceng says.

“The vaccine is a recombinant vaccine genetically developed by getting a particle of the Ebola gene, replacing a particle of the gene with another virus called the vesicular stomatitis virus. The vaccine therefore is a genetically modified organism, that is able to replicate and cause antibody production against the Ebola virus but not cause Ebola virus disease,” she explained.

Also Read:Ebola Not A Global Health Emergency: WHO

The Ebola virus causes a severe and often fatal hemorrhagic fever.

The Democratic Republic of Congo has confirmed 250 cases of Ebola — causing 180 deaths — and another 41 suspected cases. (VOA)

Next Story

Usage Of Expired Polio Vaccines Creates a Public Scare In China

Regardless of how harsh the punishments will be, what’s more important is no more faulty vaccines used on their children, many parents said.

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China, Vaccines
A child receives a vaccination shot at a hospital in Rongan in China's southern Guangxi region on July 23, 2018. VOA

A recent vaccine scandal in eastern China’s Jiangsu province, where 145 children were confirmed to have received expired polio vaccinations, has once again exposed the country’s poor vaccine management and lack of systematic regulatory oversight, a former Chinese health official said.

To eradicate such lapses, Chen Bingzhong, ex-head of China’s Health Education Research Institute, calls for a nationwide probe, in which, third-party stakeholders such as parents, lawyers or reporters should take part to ensure transparency.

“There should first be a thorough probe into the cause of the Jiangsu case, which serves as another wake-up call. But who should launch the investigation? Local health departments alone won’t work because they are the ones who cause the problem and should be held responsible. An [unbiased] third party has to be involved,” Chen said.

Expired vaccine probe

Jiangsu police, on Monday, began an investigation after the local government in the province’s Jinhu County concluded that “only 145 children” were orally administered with polio vaccines that expired on December 11, 2018.

And so far a total of 17 officials have been punished, including the deputy head of Jinhu County.

China, Vaccines

The local government has also promised check-ups on all affected children.

Tao Lina, a Shanghai-based vaccine expert, blamed the county’s online registration system, which she said failed to alert doctors about expired vaccines or registered the wrong expiration date, according to a Global Times report.

A cover-up?

But many worried parents are skeptical of the official findings and suspect a larger-scale cover-up.

The case came to light on Jan 7 when a parent — a retired hospital worker — discovered that oral vaccine given to her grandkid was nearly a month out of date, according to local media reports.

Many parents, who picked up the news on social media, followed suit to check batch numbers on their children’s vaccination history and found that expired vaccines include not only polio vaccines, but also diphtheria-tetanus-pertussis (DPT), hepatitis B and varicella.

And the problem dates back to a decade ago, which is further fueling suspicion that the majority of the county’s 20,000 children under the age of 14 may have been exposed to faulty vaccines. The case in Jinhu is the latest in a string of similar scandals in China.

Late last week, hundreds of anxious parents gathered in front of Jinhu government offices, demanding answers.

Vaccines
A doctor assists people looking for treatment for malaria at a health center. VOA

Violent scuffles

Video footage that has gone viral on the Internet showed repeated scuffles between angry crowds, besieged government officials and squads of mob police, which continued into the night.

Three parents ended up being arrested and local residents have expressed difficulty in uploading videos of the protests to social media.

On Weibo, the equivalent of Twitter in China, some urged parents in Jinhu to stay calm, but many more shared their anger.

“The government’s credibility is overdrawn and the people’s tolerance is being put to the test,” one Weibo user said.

“To be honest, our regulators are all façade with little function,” another complained.

Public outcry

Parents elsewhere complained of governments of all levels’ inaction to address the country’s vaccine problems including appropriate compensations to those who suffer adverse effects.

The Drugs Controller General of India plans to come out with vaccine specific regulatory policy and a manual for regulatory requirements for commercialization of new drug and on how to conduct clinical trials in India, it was announced on Saturday.
To eradicate such lapses, Chen Bingzhong, ex-head of China’s Health Education Research Institute, calls for a nationwide probe, Pixabay

A father from Fujian province surnamed Lin told VOA that the local government there has done nothing to help this teenaged son, who experienced severe adverse effects from vaccines at the age of three.

“They [the Fujian government] keep patronizing me and passing the buck,” he said.

“Two to three years ago, my kid was identified to be suffering adverse reactions from vaccines, which is extremely rare. If the government can help deal with it, we have nothing to complain. But it’s been ten years, the government hasn’t even tried to take up a [responsible] stance, which I find very hard to accept. My child is now in a [brain-damaged] state,” he added.

A series of vaccine scandals in China including years of illegal sales of improperly-refrigerated vaccines and locally-produced substandard vaccines, which respectively came to light in March and July last year, have seriously undermined public confidence in spite of repeated calls for tightened regulation.

Vaccine management law

Wang Yuedan, deputy director of Peking University’s immunology department, however, insisted that the Jiangsu case is an isolated misconduct of local medical staff and the upcoming passage of a law on vaccine management will help address regulatory loopholes.

Odisha
The case came to light on Jan 7 when a parent — a retired hospital worker — discovered that oral vaccine given to her grandkid was nearly a month out of date. Pixabay

To tighten supervision on vaccines, Beijing released a draft Vaccine Management Law this month and is seeking public opinions until next month.

“I believe, once the law takes effect, there will be harsher punishments [on lawbreakers] to prevent such lapses. Among past expired vaccine cases, the punishment imposed on officials [in Jinhu] this time have been the harshest-ever,” he said.

But Chen disagreed.

He asked why many people from local medical staff to regulators in Jiangsu, who are responsible of tracking vaccine flows, have failed to sound alarm bells over expired vaccines?

Also Read: China Exchanged Data With NASA On Its Recent Mission To Moon

That shows a systematic regulatory negligence — serious flaws that legal revisions alone won’t cure if few profit-driven lawbreakers and officials who helped cover up the crisis have been held responsible, he said, adding a nationwide probe will find parents in Jiangsu aren’t alone.

Regardless of how harsh the punishments will be, what’s more important is no more faulty vaccines used on their children, many parents said. (VOA)