General

Novel Stroke Treatment Repairs Damaged Brain Tissue

NewsGram Desk

Researchers have developed a new stem-cell based treatment for stroke that reduces brain damage and accelerates the brain's natural healing tendencies.

The treatment called AB126 was developed using extracellular vesicles (EV) — fluid-filled structures known as exosomes — which are generated from human neural stem cells.

"This is truly exciting evidence because exosomes provide a stealth-like characteristic, invisible even to the body's own defenses. When packaged with therapeutics, these treatments can actually change cell progression and improve functional recovery," said Steven Stice, a professor at the University of Georgia in the US who led the research team.

Fully able to cloak itself within the bloodstream, this type of regenerative EV therapy appears to be the most promising in overcoming the limitations of many cells therapies-with the ability for exosomes to carry and deliver multiple doses-as well as the ability to store and administer treatment, the researchers said.

Human clinical trials for the treatment could begin as early as next year, the researchers added. Pixabay

Small in size, the tiny tubular shape of an exosome allows EV therapy to cross barriers that cells cannot, said the study published in the journal Translational Stroke Research.

Following the administration of AB126, the researchers used MRI scans to measure brain atrophy rates in preclinical, age-matched stroke models, which showed an approximately 35 percent decrease in the size of injury and 50 percent reduction in brain tissue loss.

"Until now, we had very little evidence specific to neural exosome treatment and the ability to improve motor function. Just days after stroke, we saw better mobility, improved balance, and measurable behavioral benefits in treated animal models," Stice said.

Human clinical trials for the treatment could begin as early as next year, the researchers added. (IANS)

NewsGram Digital Media Certification Program ( 2 months)

NewsGram invites you to join our exclusive Certification Program designed to help you excel in Journalism and Content Creation! The successful completion of this Digital Media Certification Program will empower you with hands on skills of new media (digital journalism).

Mode of administration: Online (remote)

Duration: 2 months

What You Get:

✅ Author Profile / Byline – Your own author page on NewsGram📝

✅ Certificate – Official recognition of your expertise 🎓

✅ Live Classes – Weekend sessions + One-on-one sessions on weekdays 🎥👨‍🏫

✅ Article Publication – Publish for free under expert mentorship 📰✍️

✅ Freelancing Opportunity – Potential to work with NewsGram in the future 💼🚀

Apply right now with a mail on education@newsgram.com

Click here for more detail about the Course.

Delhi Man Arrested for Killing Wife, Mother-in-Law Following Gift Dispute at Son’s Birthday

Why the pani puri platter remains India’s favourite snack

Trump’s Tariff Hike Fuels India’s ‘Go Swadeshi’ Push; McDonald’s, Pepsi Risk Losing Key Market

The invisible hands that bury Kashmir’s dead

A pill to change gut microbiome key to fight obesity, related heart disease & diabetes risk