Tuesday June 18, 2019

Hearing Loss Can Effect Your Memory

According to a 2016 study published in the Indian Journal of Otolaryngology and Head and Neck Surgery, 63 million people (6.3 per cent) suffer from significant auditory loss in India.

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Structure of brain can help find the causes behind epilepsy.
Structure of brain can help find the causes behind epilepsy.

Hearing loss can lead to impaired memory and higher risk of dementia and ensuing Alzheimer’s disease in older people, health experts say.

Deafness, according to the World Health Organisation (WHO), refers to the complete loss of hearing ability in one or both ears, while “hearing impairment” refers to both complete and partial loss of hearing ability.

Nearly 360 million people, nearly one-tenth of them children, suffer from hearing loss worldwide.

“Yes, hearing loss can lead to cognitive decline. Our two senses — vision and hearing — contribute to our cognitive development. When we are not able to hear well, most of the information that is delivered to us that way is not received properly. This way, less hearing slowly contributes to cognitive decline,” Suresh Singh Naruka, Senior Consultant – ENT at Indraprastha Apollo Hospitals here, told IANS.

Concussion without loss of consciousness led to 2.36 times the risk for dementia, showed the findings published in the journal JAMA Neurology.
Head blows can cause dementia, Pixabay

“It is important to understand that brain development and cognition development is a slow process. Intelligence is not a static thing; it is a dynamic and continuous process. It may not be visible in a day or two, but over a period of time one can witness the decline in cognitive behaviour,” Naruka added.

A study led by researchers at Brigham and Women’s Hospital in the US suggests that hearing loss is associated with new onset of subjective cognitive concerns which may be indicative of early stage changes in cognition.

The study, published in the Alzheimer’s and Dementia journal, examined 10,107 men aged 62 years.

The team found that compared with men with no hearing loss, the relative risk of cognitive decline was 30 per cent higher among men with mild hearing loss, 42 per cent higher among men with moderate hearing loss and 54 per cent higher among men with severe hearing loss but who did not use hearing aids.

The findings may help identify individuals at greater risk of cognitive decline.

It may help identify individuals at greater risk of cognitive decline and could provide insights for earlier intervention and prevention, the researchers said.

Moreover, “while hearing loss can lead to impaired memory and higher risk of dementia in older people, in children it hampers with development of speech and brain development”, Virender Singh, Consultant – ENT, Fortis Hospital, Shalimar Bagh, told IANS.

According to a 2016 study published in the Indian Journal of Otolaryngology and Head and Neck Surgery, 63 million people (6.3 per cent) suffer from significant auditory loss in India.

Four in every 1,000 children suffer from severe to profound hearing loss in India. With over 100,000 babies that are born with hearing deficiency every year, the estimated prevalence of adult-onset deafness in India was found to be 7.6 per cent and childhood-onset deafness to be 2 per cent.

“Hearing loss is a much neglected phenomenon in our country. Congenital deafness or any neonatal disease such as prolonged jaundice, meningitis or prolonged labour leading to delayed oxygenation can cause mild to profound hearing loss in neonate,” Singh said.

Depression related to brain mechanism.
Depression related to brain mechanism. IANS

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Hearing loss in children can hamper the development of speech and the brain. This can lead to shutting the child from worldly sounds, resulting in a disconnect from the social world.

“Early corrective measures in the form of hearing aid, cochlear implant, medications and corrective surgery should be taken as soon as possible to prevent any complications that arise from hearing loss,” Singh suggested. (IANS)

Next Story

It is Now Possible to Reverse Memory Loss Caused by Alzheimer’s, Says Study

Future studies will focus on developing compounds that penetrate the brain more effectively and are thus longer-lasting, the researchers said

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In Alzheimer's disease, patients start losing memory. Pixabay

Researchers have developed a novel approach that may one day make it possible to reverse memory loss, caused by Alzheimer’s disease.

The team, led by University at Buffalo scientists, found that by focusing on gene changes caused by influences other than DNA sequences — called epigenetics — it was possible to reverse memory decline in an animal model of Alzheimer’s.

“We have not only identified the epigenetic factors that contribute to the memory loss, but we also found ways to temporarily reverse them in an animal model of Alzheimer’s,” said Zhen Yan, Professor at University at Buffalo in the US.

The research, published in the journal Brain, was conducted on mouse models carrying gene mutations for familial Alzheimer’s — where more than one member of a family has the disease — and on post-mortem brain tissues from Alzheimer’s patients.

alzheimer's, cholesterol
Poor sleep can predict Alzheimer’s Risk in elderly. Pixabay

Alzheimer’s is caused from both genetic and environmental risk factors, such as ageing, which combine to result in epigenetic changes, leading to gene expression changes, but little is known about how that occurs.

The epigenetic changes in Alzheimer’s happen primarily in the later stages, when patients are unable to retain recently learned information and exhibit the most dramatic cognitive decline, Yan said.

A key reason for the cognitive decline is the loss of glutamate receptors, which are critical to learning and short-term memory.

The researchers found that the loss of glutamate receptors is the result of an epigenetic process known as repressive histone modification, which is elevated in Alzheimer’s.

“Our study not only reveals the correlation between epigenetic changes and Alzheimer’s, we also found we can correct the cognitive dysfunction by targeting the epigenetic enzymes to restore glutamate receptors,” Yan said.

A lady suffering from Alzheimer’s. Flickr

The Alzheimer’s animals were injected three times with compounds designed to inhibit the enzyme that controls repressive histone modification.

In animals who received the enzyme inhibitor the cognitive function restored and was confirmed through evaluations of recognition memory, spatial memory and working memory.

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The improvements lasted for one week. Future studies will focus on developing compounds that penetrate the brain more effectively and are thus longer-lasting, the researchers said. (IANS)